2023

Cseh K., Berasaluce I., Fuchs V., Banc A., Schweikert A., Prado-Roller A., Hejl M., Wernitznig D., Koellensperger G., Jakupec MA., Kandioller W., Malarek MS., Keppler BK., Anticancer Tungstenocenes with a Diverse Set of (O,O-), (O,S-) and (O,N-) Chelates-A Detailed Biological Study Using an Improved Evaluation via 3D Spheroid Models. Pharmaceutics, 2023 Jul 3;15(7):1875, DOI: 10.3390/pharmaceutics15071875.

Iriarte-Mesa C., Jobst M. Bergen J., Kiss E., Ryoo R., Kim J.-C., Crudo F., Marko D., Kleitz F., Del Favero G., Morphology-Dependent Interaction of Silica Nanoparticles with Intestinal Cells: Connecting Shape to Barrier Function, Nano Letters, July 11, 2023, DOI: 10.1021/acs.nanolett.3c00835 

Buchacher T., Digruber A., Kanzler M., Del Favero G., Ehling-Schulz M., Bacillus cereus extracellular vesicles act as shuttles for biologically active multicomponent enterotoxins, Cell Communication and Signaling, 2023 May 15, DOI: 10.1186/s12964-023-01132-1

Bergen J., Karasova M., Bileck A., Pignitter M., Marko D., Gerner Ch., Del Favero G., Exposure to dietary fatty acids oleic and palmitic acid alters structure and mechanotransduction of intestinal cells in vitro, Archives of Toxicology, April 29, 2023, DOI:10.1007/s00204-023-03495-3

Hlaoperm Ch., Sudjarwo W.A.A., Ehrenbrandtner J., Kiss E., Del Favero G., Choowongkomon K., Rattanasrisomporn J., Lieberzeit P.A., Molecularly Imprinted Nanoparticle Ensembles for Rapidly Identifying S. epidermidis, Sensors, 2023 Mar 28, DOI: 10.3390/s23073526.

2022

Jobst M., Kiss E., Gerner Ch., Marko D., Del Favero G., Activation of autophagy triggers mitochondrial loss and changes acetylation profile relevant for mechanotransduction in bladder cancer cells, Archives of Toxicology, October 10, 2022, DOI: 10.1007/s00204-022-03375-2

Rebhahn V.I.Ch., Kiss E., Marko D., Del Favero G., Foodborne compounds that alter plasma membrane architecture can modify the response of intestinal cells to shear stress in vitro, Toxicology and Applied Pharmacology, Volume 446, 1 July 2022, DOI: 10.1016/j.taap.2022.116034

Groestlinger J., Seidl C., Varga E., Del Favero G., Marko D., Combinatory Exposure to Urolithin A, Alternariol, and Deoxynivalenol Affects Colon Cancer Metabolism and Epithelial Barrier Integrity in vitro, Frontiers in Nutrition, June 24, 2022, DOI: 10.3389/fnut.2022.882222

Hohagen M., Guggenberger P., Kiss E., Kählig H., Marko D., Del Favero G., Kleitz F., TANNylation of Mesoporous Silica Nanoparticles and Bioactivity Profiling in Intestinal Cells, Journal of Colloid and Interface Science, May 10, 2022, DOI: 10.1016/j.jcis.2022.05.035

Von Baeckmann C., Riva A., Guggenberger P., Kählig H., Won Han S., Inan D., Del Favero G., Berry D., Kleitz F., Targeting Gut Bacteria Using Inulin-Conjugated Mesoporous Silica Nanoparticles, Advanced Materials Interfaces, April 17, 2022, DOI: 10.1002/admi.202102558

Groestlinger J., Spindler V., Pahlke G., Rychlik M., Del Favero G., Marko D., Alternaria alternata Mycotoxins Activate the Aryl Hydrocarbon Receptor and Nrf2-ARE Pathway to Alter the Structure and Immune Response of Colon Epithelial Cells, ACS Chemical Research in Toxicology, April 11, 2022, DOI: 10.1021/acs.chemrestox.1c00364

Crudo F., Aichinger G., Dellafiora L., Kiss E., Mihajlovic J., Del Favero G., Berry D., Dall’Asta Ch., Marko D., Persistence of the antagonistic effects of a natural mixture of Alternaria mycotoxins on the estrogen-like activity of human feces after anaerobic incubation, Toxicology Letters, Vol 358, April 2022, DOI: 10.1016/j.toxlet.2022.01.015

Allahyarli K., Reithofer M.R., Cheng F., Young A.J., Kiss E., Tsai Yuan Tan T., Prado-Roller A., Chin J.M., Metal-Organic Framework superstructures with long-ranged orientational order via E-field assisted liquid crystal assembly, Journal of Colloid and Interface Science, Volume 610, 15 March 2022, Pages 1027-1034, DOI: 10.1016/j.jcis.2021.11.151

Bileck A., Bortel P., Kriz M., Janker L., Kiss E., Gerner Ch., Del Favero G., Inward Outward Signaling in Ovarian Cancer: Morpho-Phospho-Proteomic Profiling Upon Application of Hypoxia and Shear Stress Characterizes the Adaptive Plasticity of OVCAR-3 and SKOV-3 Cells, frontiers in Oncology, 14 February 2022 | DOI: 10.3389/fonc.2021.746411

Beisl J., Pahlke G., Ehling-Schulz M., Del Favero G., Marko D., Cereulide and Deoxynivalenol Increase LC3 Protein Levels in HepG2 Liver Cells, Toxins, Feb. 18, 2022, DOI: 10.3390/toxins14020151

2021

Del Favero G., Aichinger G., Hohenbichler J., Marko D., Dall’Asta Ch., Dellafiora L., A target fishing study to spot possible biological targets of fusaric acid: Inhibition of protein kinase-A and insights on the underpinning mechanisms, Food and Chemical Toxicology, Nov. 5, 2021, DOI: 10.1016/j.fct.2021.112663

Rusz M., Del Favero G., El Abiead Y., Gerner C., Keppler B., Jakupec M., Koellensperger G., Morpho-metabotyping the oxidative stress respons, Scientific Reports, 2021 Jul 29;11(1):15471. doi: 10.1038/s41598-021-94585-8

Del Favero G., Zeugswetter M., Kiss E., Marko D., Endoplasmic Reticulum Adaptation and Autophagic Competence Shape Response to Fluid Shear Stress in T24 Bladder Cancer Cells, frontiers in Pharmacology, 03 May 2021, DOI: 10.3389/fphar.2021.647350

Del Favero G., Janker L., Neuditschko B., Hohenbichler J., Kiss E., Woelflingseder L., Gerner Ch., Marko D., Exploring the dermotoxicity of the mycotoxin deoxynivalenol: combined morphologic and proteomic profiling of human epidermal cells reveals alteration of lipid biosynthesis machinery and membrane structural integrity relevant for skin barrier function, Archives of Toxicology, 2021 Apr. 1, doi: 10.1007/s00204-021-03042-y

Beisl J., Varga E., Braun D., Warth B., Ehling-Schulz M., Del Favero G., Marko D., Assessing Mixture Effects of Cereulide and Deoxynivalenol on Intestinal Barrier Integrity and Uptake in Differentiated Human Caco-2 Cells, Toxins, 2021 March, DOI: 10.3390/toxins13030189

Niederstaetter L., Neuditschko B., Brunmair J., Janer L., Bileck A., Del Favero G., Gerner Ch., Eicosanoid Content in Fetal Calf Serum Accounts for Reproducibility Challenges in Cell Culture, Biomolecules, 2021 Jan 15;11(1):113. doi: 10.3390/biom11010113.

2020

Wernitznig D., Meier-Menches S.M., Cseh K., Theiner S., Wenisch D., Schweikert A., Jakupec M.A., Koellensperger G., Wernitznig A., Sommergruber W., Keppler B., Plecstatin-1 induces an immunogenic cell death signature in colorectal tumour spheroids, Metallomics, Volume 12, Issue 12, December 2020, Pages 2121–2133, DOI: 10.1039/d0mt00227e

Meier-Menches S.M., Neuditschko B., Zappe K., Schaier M., Gerner M.C., Schmetterer K.G., Del Favero G., Bonsignore R., Cichna-Markl M., Koellensperger G., Casini A., Gerner Ch., An Organometallic Gold(I) Bis-N-Heterocyclic Carbene Complex with Multimodal Activity in Ovarian Cancer Cells, Chemistry, 2020 Dec 1;26(67):15528-15537. doi: 10.1002/chem.202003495

Harringer S., Wernitznig D., Gajic N.,  Diridl A., Wenisch D., Hejl M., Jakupec M.A., Theiner S., Koellensperger G., Kandioller W., Keppler B.K., Introducing N-, P-, and S-donor leaving groups: an investigation of the chemical and biological properties of ruthenium, rhodium and iridium thiopyridone piano stool complexes, Dalton Transactions, Nov. 2, 2020, DOI: 10.1039/D0DT03165H

Del Favero G., Bonifacio A., Rowland T. J., Gao Sh., Song K., Sergo V., Adler E. D., Mestroni L., Sbaizero O., Taylor M. R. G., Danon Disease-Associated LAMP-2 Deficiency Drives Metabolic Signature Indicative of Mitochondrial Aging and Fibrosis in Cardiac Tissue and hiPSC-Derived Cardiomyocytes, Journal of Clinical Medicine, 2020 Jul 31;9(8):E2457. doi: 10.3390/jcm90824

Hohenbichler J., Aichinger G., Rychlik M., Del Favero G., Marko D., Alternaria alternata Toxins Synergistically Activate the Aryl Hydrocarbon Receptor Pathway In Vitro, Biomolecules 2020, 10(7), 1018, July 9, 2020, DOI: 10.3390/biom10071018

Juère E., Del Favero G., Masse F., Marko D., Popat A., Florek J., Caillard R., Kleitz F., Gastro-protective protein-silica nanoparticles formulation for oral drug delivery: in vitro release, cytotoxicity and mitochondrial activity, European Journal of Pharmaceutics and Biopharmaceutics, 2020 June. pii: S0939-6411(20)30082-5. doi: 10.1016/j.ejpb.2020.03.015

Aichinger G., Dellafiora L., Pantazi F., Del Favero G., Galaverna G., Dall'Asta C., Marko D., Alternaria toxins as casein kinase 2 inhibitors and possible consequences for estrogenicity: a hybrid in silico/in vitro study, Archives of Toxicology, 2020 June, doi: 10.1007/s00204-020-02746-x

Gerner M.C., Ziegler L.S., Schmidt R.L.J., Krenn M., Zimprich F., Uyanik-Ünal K., Konstantopoulou V., Derdak S., Del Favero G., Schwarzinger I., Boztug K., Schmetterer K.G., The TGF-b/SOX4 axis and ROS-driven autophagy co-mediate CD39 expression in regulatory T-cells, FASEB Journal, 2020 June, doi: 10.1096/fj.201902664

Del Favero G., Kraegeloh A., Integrating Biophysics in Toxicology, Cells, 2020 May 21;9(5):E1282. doi: 10.3390/cells9051282

Juère E., Caillard R., Marko D., Del Favero G., Kleitz F., Smart protein-based formulation of dendritic mesoporous silica nanoparticles: Toward oral delivery of insulin, Chemistry, 2020 Apr. 21. doi: 10.1002/chem.202000773

Aichinger G., Lichtenberger F.B., Steinhauer T.N., Flörkemeier I., Del Favero G., Clement B., Marko D., The Aza-Analogous Benzo[c]phenanthridine P8-D6 Acts as a Dual Topoisomerase I and II Poison, thus Exhibiting Potent Genotoxic Properties, Molecules. 2020 Mar 27;25(7). pii: E1524. doi: 10.3390/molecules25071524.

Del Favero G., Mayer R.M., Dellafiora L., Janker L., Niederstaetter L., Dall'Asta C., Gerner C., Marko D., Structural Similarity with Cholesterol Reveals Crucial Insights into Mechanisms Sustaining the Immunomodulatory Activity of the Mycotoxin Alternariol, Cells, 2020 Mar 31;9(4). pii: E847. doi: 10.3390/cells9040847

Beisl J., Pahlke G., Abeln H., Ehling-Schulz M., Del Favero G., Varga E., Warth B., Sulyok M., Abia W., Ezekiel CN., Marko D., Combinatory effects of cereulide and deoxynivalenol on in vitro cell viability and inflammation of human Caco-2 cells, Archives of Toxicology, 2020 March doi: 10.1007/s00204-020-02658-w

Neuditschko B., Janker L., Niederstaetter L., Brunmair J., Krivanek K., Izraely S., Sagi-Assif O., Meshel T., Keppler B., Del Favero G., Witz I.P., Gerner C., The challenge of classifying metastatic cell properties by molecular profiling exemplified with cutaneous melanoma cells and their cerebral metastasis from patient derived mouse xenografts, Molecular & Cellular Proteomics, 2020 March, pii: mcp.RA119.001886. doi: 10.1074/mcp.RA119.001886

Muqaku B., Pils D., Mader J.C., Aust S., Mangold A., Muqaku L., Slany A., Del Favero G., Gerner Ch., Neutrophil extracellular trap formation correlates with improved overall survival in ovarian cancer, Cancers (Basel), 2020 Feb 21;12(2). pii: E505. doi: 10.3390/cancers12020505.

Del Favero G., Hohenbichler J., Mayer R.M., Rychlik M., Marko D., Mycotoxin Altertoxin II Induces Lipid Peroxidation Connecting Mitochondrial Stress Response to NF-κB Inhibition in THP-1 Macrophages, Chemical Research in Toxicology, 2020 Feb, doi: 10.1021/acs.chemrestox.9b00378